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Fundamentals of Nursing - Chapter 2. 18 terms. marygracewatson12. Preview. Terms in this set (31)Renal failure is a systemic disease and is a final common pathway of many different kidney and urinary tract diseases. Accumulation. As renal function declines, the end products of protein metabolism (normally excreted in urine) accumulate in the blood. Adverse effects. Uremia develops and adversely affects every system in the body.4.8/5. 100% Success rate. Level: Master's, University, College, PHD, High School, Undergraduate. NursingManagementBusiness and EconomicsCommunications and Media+96. 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